Monday, October 31, 2005

Rosacea And Red Wine Headaches

Many people get headaches from red wine, and what causes it exactly is a little bit of a mystery. But the condition is so common there’s even a name for it – Red Wine Headache. You heard us: If you get headaches from red wine, you may be suffering from RWH.

Sulfites get the blame for the headaches most often. But it turns out only about 1 percent of the population is truly allergic to sulfites, which are found in most wines – red and white. And because sulfites act as a preservative, you’ll find them in a lot more places than just your favorite bottle of wine.

If you can eat dried fruit and guacamole without a problem, you likely don’t have a sulfite allergy. And if your only symptom is a headache, that’s another sign you’re not allergic to sulfites. Those allergic to sulfites will also experience coughing, wheezing, itching and even hives.

If that’s not happening to you, it’s probably something else in the wine that’s bothering you. Some people blame the tannins found in red wine. Tannins come from the grapes and their skin and act as a natural preservative for the wine. It’s why red wines often have the ability to age longer than white wines.

But studies haven’t been able to prove that tannins cause headaches. In fact, said University of California-Davis wine chemist Dr. Andy Waterhouse, studies have proved that lots of things do not cause red wine headaches – but no one knows what does.

“I haven’t heard of anything that can actually explain it,” Waterhouse said. “There’s plenty of data that shows it’s real – they’re not just drinking too much. There’s something real going on, but the cause is not known.”

Waterhouse said most of the suspected causes – everything from sulfites to histamines – have been disproved.

So what is it then that’s causing your head to pound? Well, some suspect it might be something called “congeners,” which appear in most alcoholic beverages. Congeners are a byproduct of fermentation and have higher concentrations in darker alcohols, like red wine.

Waterhouse said the congeners theory is a new one to him, but the search for the cause continues.

Now that you know this, what can you do about it? Well, there are a few remedies on the market, but nothing we’ve tried. Fortunately, we don’t suffer from RWH.

If you’re willing to suffer a few headaches in the name of research, it might be interesting to know whether certain red wines, like cabernet sauvignon, cause worse headaches than lighter reds, like pinot noir, or whether there is a threshold, like one glass is OK but two triggers a migraine. If you’ve got something that works for you, let us know and we’ll pass it along to 100,000 of our closest friends.

Another red wine ailment people often complain about is having their lips or teeth turn blue or purple after a glass or two or six.

Now this one, we can tell you about from personal experience. We went to Rome a few years ago where wine is cheaper than water. (Bottled water was $3.50, while a half-liter of wine was $3. Trust us, we miss Rome.) So, of course, with every meal, a glass of wine or two is standard. Well, not breakfast – but definitely brunch.

By the end of the trip – OK, just a few days into the trip – Krista’s lips were stained dark purple. It was a little disconcerting, but worth it for the great wine we had.

What caused it? The same thing that causes wine to have its color in the first place – the compounds in the grape skins. Just like soaking the skins in the juice during fermentation makes red wine deep ruby, soaking your lips in a glass can eventually have the same effect. Finally, many people have asked us why their faces get flushed when they drink wine – particularly red wine. Well, we know that drinking alcohol thins the blood and those suffering from Rosacea, a condition that causes the skin to turn red, have a hard time with red wine.

But we don’t know why red would do that to some people more so than white wine, except that red wines tend to be slightly higher in alcohol than whites, with some blockbuster reds approaching 15 percent.

The fact is, the chemistry of wine is complicated, and even though humans have been making wine for thousands of years, there’s still much we don’t know about it. Researchers such as Waterhouse have dedicated their entire careers to exploring the chemical mysteries of fermented grape juice.

We may not understand it all – it seems like every week a new report on the health benefits of wine is published – but we know we love drinking it. And in the end, that’s what really matters.

Friday, October 21, 2005

Rosacea And The Seborrheic Dermatitis Connection

Patients with Rosacea often have seborrheic dermatitis which co-exist in 35% of sufferers which makes for a most delicate skin condition; and even more so when adult acne co-exist with rosacea in approximately 82% of sufferers. The combination of the three is quite aggravating as seen by years of past efforts, the treatment of one condition aggravates the other two medical conditions. So does one condition cause or  create circumstances to promote the occurrence of the other? The answer is hard to say, over treatment of seborrhea dermatitis can cause sensitivity to the skin leading to a higher risk of rosacea.

Monday, October 17, 2005

The Inflammatory Picture of Rosacea

Rosacea is an inflammatory skin condition that causes redness of the face. You may mistake some of its characteristics — small, red, pus-filled bumps or pustules — for acne. In fact, rosacea has been called adult acne or acne rosacea. Even though some people with rosacea had acne as teenagers, the disorder has little to do with the pimples and blackheads that commonly afflict teenagers. The cause of rosacea remains unknown.

Rosacea affects mostly adults, usually people with fair skin, between the ages of 30 and 60. About 14 million Americans have this skin condition. Although it's more common in women, men may develop more apparent signs of the disorder. It's not life-threatening, but it can affect your appearance and self-esteem.

Left untreated, rosacea tends to be progressive, which means it gets worse over time. However, in most people rosacea is cyclic, which means it may flare up for a period of weeks to months and then signs and symptoms lessen for a while before rosacea flares up again. Besides acne, rosacea can also be mistaken for other skin problems, such as skin allergy or eczema. Once diagnosed, it's quite treatable.

Friday, October 14, 2005

The Picture of Rosacea's Signs And Symptoms

Rosacea may begin as a tendency to flush or blush easily. In fact, when people with rosacea think about their pasts, they often remember flushing or blushing more easily than most. This tendency to flush or blush easily can occur over a long period of time and may gradually progress to a persistent redness, pimples and visible blood vessels in the center of the face that can eventually involve the cheeks, forehead, chin and nose. Other affected areas may be the neck, ears, chest and back.

About half the people who have rosacea develop ocular rosacea.

While most common on the face, one recent study indicated that some people who have rosacea do not have it on their face at all but rather on their back or elsewhere. 1


Signs and symptoms vary from person to person and are often intermittent. If you or someone you know exhibits any of the following, it is best to consult a dermatologist. Rosacea can be treated and controlled if medical advice is sought in the early stages. When left untreated, rosacea often gets worse and then becomes more difficult to treat.

Rosacea can cause redness, similar to that of a blush or sunburn. The flushing occurs when increased amounts of blood flow through vessels at a fast rate and the vessels expand to accommodate this flow. The redness may become more noticeable and persistent as the disease progresses.

Some people notice that their facial skin becomes increasingly dry.

The pimples of rosacea, which often occur as the disease progresses, are
different from those of acne because blackheads and whiteheads
(known as comedones) rarely appear. Rather, people with rosacea have visible small blood vessels and their pimples—some containing pus—appear as small, red bumps.

Some with rosacea notice red lines, called telangiectasia (tell-an-jek-taze-yah), which appear when they flush. This is due to small blood vessels of the face becoming enlarged and showing through the skin. These red lines usually appear on the cheeks—especially when the overall redness diminishes.

Nasal bumps, a condition called rhinophyma (rye-no-feye-muh), are an uncommon sign seen especially in untreated rosacea. Men are more likely to experience the small, knobby bumps on the nose, and as the number of bumps increases, the nose and cheeks
may appear swollen.

A 2002 survey conducted by the National Rosacea Society indicated that some people who have rosacea suffer physical symptoms, such as facial burning, stinging or itching.

Wednesday, October 12, 2005

Rosacea Allocation Grant

Grant Allocation Announcement
12th October 2005

The Rosacea Research Foundation has allocated 2005 donated funds to an excellent grant.

STRUCTURAL AND BIOLOGIC CHANGES IN ROSACEA SKIN INDUCED BY PULSE DYE LASER AND INTENSE PULSED LIGHT

Dr. Payam Tristani-Firouzi, Assistant Professor,
Dr. Nancy Samolitis, Visiting Professor,
Department of Dermatology,
University of Utah School of Medicine.

Drs. Tristani and Samolitis plan to examine the effect of pulse dye laser (PDL) and intense pulsed light (IPL) treatment of rosacea to determine whether, in addition to reducing the amount of blood vessels, these procedures produce structural and biologic change in the skin that may help identify and increase understanding of the causes of this disorder.

The researchers will visually and microscopically assess the primary features of rosacea before and after treatment with PDL and IPL, including redness (erythema), visible blood vessels (telangiectasia), bumps
(papules) and pimples (pustules).

In addition, biopsy samples before and after treatment will be tested for factors that are increasingly recognized as playing a potential role in the development of rosacea. These will include the presence of
inflammatory cells (perifollicular inflammatory infiltrate), vascular endothelial growth factor (VEGF), interleukin-1 (IL-1) and factor XIII.

The researchers will also assess the size of oil (sebaceous) glands and the presence of Demodex mites, a normal inhabitant of human skin that has been observed in greater numbers in rosacea patients.

The study will include 10 patients with subtype 1 (erythematotelangiectatic) rosacea and subtype 2 (papulopustular) rosacea, each received treatment on one side of the face with the other side
serving as a control. The overall severity of these signs of rosacea will
also be evaluated by the patients.

Monday, October 10, 2005

Changes in The Rosacea Research Picture

From: David Pascoe [david.pascoe@rosacea-research.org]
To: rosacea-research-foundation@yahoogroups.com
Sent: Mon 10/10/2005 7:39 PM

The Rosacea Research Foundation is pleased to announce that our funds have
been allocated to a grant.

The grant will be allocated to a study called "Structural and biologic
changes in the rosacea skin induced by pulse dye laser and intense pulsed
light". The grant has been awarded to Drs. Payam Tristani-Firouzi and
Nancy Samolitis.

Dr. Chuck Young, Artist Cloutier and David Pascoe would personally like to
thank the following for their expert opinion in reviewing and ultimately
approving this grant.

Rosacea Research Foundation Medical Advisory Committee

Dr. Linda Sy
Board Certified Dermatologist
Linda Sy Skincare

Dr. Nicholas Soldo
Anaesthetist & IPL Consultant

Dr. Peter Drummond
Associate Professor,
School of Psychology
Murdoch University

Dr. Chuck Young
Vice President
Rosacea Research Foundation

Friday, October 07, 2005

THE RED FACE OF GEOFFREY NASE

Rosacea guru to end battle over critics' site
By Kevin Corcoran
kevin.corcoran@indystar.com
A Fishers physiologist whose online postings turned him into a guru for people suffering from rosacea agreed Thursday to abandon his legal fight to silence a Web site questioning his credentials and advice.

Published anonymously, the site claims Geoffrey Nase, 36, is practicing medicine without a license and dispensing potentially harmful advice to many thousands of people desperately seeking a cure for the tough-to-treat inflammatory skin disease.

Nase -- who has made claims about himself that Indiana medical groups have refuted -- unmasked his cybercritics, and Thursday he tried to confront them in Marion Superior Court.
After several hours of attorneys for the Web site operators and Nase shuttling in and out of Judge Kenneth Johnson's office, both sides said they had reached an agreement in principle.
Nase's attorney, Vincent Perez, described it as a confidential settlement. However, Ronald J. Waicukauski, the attorney for the out-of-state Web site operators, said his clients would continue to maintain their online presence and that Nase agreed to drop his lawsuit by Jan. 31.
In court filings, Nase claims his online rosacea critics slandered him, interfered in his business pursuits and dried up sales of his self-published, 332-page book on the incurable and progressive acnelike disease. He had asked Johnson to order the Web site shut down immediately.

Nase has stated he filed the suit in mid-August to defend his reputation. The case would have required Johnson to balance the critics' First Amendment rights against the potential harm to Nase's Internet business prospects.

The defendants -- Dr. Nicholas Soldo, an anesthesiologist from Scottsdale, Ariz., who uses lasers to treat rosacea, and one of Soldo's former patients, Laura Thomas, Asheville, N.C. -- say they can back up claims that Nase has inflated his credentials and dispensed harmful advice.
Both attended what was supposed to be a full-blown evidentiary hearing Thursday.
"Under no circumstances was that Web site coming down," Soldo said after the closed-door settlement talks. "It's too important to the rosacea community."

Online, the flare-ups between Nase and his critics have been dubbed the "Rosacea Wars" or "Nase wars" because of the way the caustic exchanges have roiled chat boards devoted to the disease.

Johnson said he did an online search during the settlement talks he initiated and found at least 10 pages of back-and-forth.

"I said, 'Geez, you guys have been really, really busy,' " Johnson said.

Nase estimates he has personally posted 55,000 individual messages touting rosacea research and offering free advice to sufferers within the past nine years. In addition, he ships his self-published paperback, "Beating Rosacea: Vascular, Ocular & Acne Forms," directly from his office for $46.90 plus shipping and handling, according to Amazon.com.

Nase has a doctoral degree in microvascular physiology from West Virginia University's School of Medicine. Nase runs an online site called "drnase.com" for rosacea sufferers looking for alternative treatments.

Waicukauski told the court Nase "has ruthlessly attacked virtually anyone who disagrees with him." Soldo and Thomas are both ex-supporters of Nase who created the "DebunkingNase" Web site to challenge Nase's various claims.

They say they began to have doubts about him after he told his online supporters of a series of medical calamities this spring that included five gastrointestinal surgeries, the loss of 45 percent of his blood, heart attacks, major brain surgeries and a blood infection.
Yet, they say, Nase soon was back online. He even claimed to have done a business deal while in a coma.

During a deposition Sept. 30, Nase refused to answer questions about his medical treatment. He asked Johnson to block access to his medical records.
Thomas said she began checking other online claims Nase had made and uncovered inconsistencies in his background.

For instance, Nase has stated that "after detailed interviews and evaluation," Indiana's Medical Licensing Board had "granted Dr. Geoffrey Nase full privileges to offer in-depth consultations to rosacea sufferers." However, Michael Rinebold, the board's director, said Nase's claim is false.
Nase also has stated the Indiana State Medical Association gave him approval to call himself a rosacea specialist, to consult with patients over the Internet and to dispense medical advice. "I can tell you point-blank that is a bold-faced lie," said Adele Lash, the association's spokeswoman.

Nase did not return a call to his home Thursday seeking comment after the settlement was reached.

He has said his critics launched their Internet site after learning that he would be partnering with a dermatologist in Portland, Ore., who offers laser treatments for rosacea that would compete with Dr. Soldo's national practice. Nase received $6,000 a month for referring people to the Oregon clinic -- a financial tie that critics say he failed to disclose.

Nase's online detractors say the arrangement -- and his decision to seek damages against the "DebunkingNase" site operators for lost income -- ran counter to online assertions that he has "never ever made a single penny for anything related to rosacea."

Monday, October 03, 2005

The Pre-Rosacea Picture

Dermatologists now recognize an early prelude to rosacea termed pre-rosacea. Pre-rosacea is the earliest noticeable stage of rosacea. Signs of this early stage of rosacea include frequent episodes of flushing or redness of the face and/or neck that come and go. Things that can cause an episode are exposure to the sun, emotional stress, alcohol, spicy foods, exercise, cold wind, hot foods and beverages, and hot baths. Again, each person is different and what might affect one person might not bother the next.